产品货号：
Z27685
中文名称：
SREBF1抗体
英文名称：
Anti-SREBF1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SREBF1 Antibody |
| 指标别名 | bHLHd1;SREBF1;SREBP 1;SREBP1 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICC/IF,IP,Direct ELISA |
| 基因名称 | SREBF1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human SREBF1 recombinant protein (Position:E3-A330). |
| 实际分子量 | 125KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | This gene encodes a basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor that binds to the sterol regulatory element-1 (SRE1),which is a motif that is found in the promoter of the low density lipoprotein receptor gene and other genes involved in sterol biosynthesis.The encoded protein is synthesized as a precursor that is initially attached to the nuclear membrane and endoplasmic reticulum.Following cleavage,the mature protein translocates to the nucleus and activates transcription.This cleaveage is inhibited by sterols.This gene is located within the Smith-Magenis syndrome region on chromosome 17.Alternative promoter usage and splicing result in multiple transcript variants,including SREBP-1a and SREBP-1c,which correspond to RefSeq transcript variants 2 and 3,respectively. |
| Uniprot ID | P36956 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 ImmunoPrecipitation (IP) 1:50 Direct ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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